Calcium channel blockers are a class of drugs that block the entrance of calcium into the muscle cells of the heart and the arteries. It is the entrance of calcium into these cells that causes the heart to contract and arteries to narrow. Through blocking the entry of calcium, CCBs decrease contraction of the heart and dilate (widen) the arteries.
In order to pump blood, the heart request oxygen. The harder the heart works, the extra oxygen it requires. Angina (heart pain) occurs when the supply of oxygen to the heart is insufficient for the amount of work the heart must do. By dilating the arteries, CCBs decrease the pressure in the arteries. This makes it easier for the heart to pump blood, and, as a result, the heart needs a lesser amount of oxygen. Through reducing the heart's need for oxygen, CCBs relieve or prevent angina. CCBs also are used for treating high blood pressure since their blood pressure-lowering effects. CCBs also slow the rate at which the heart beats and are then used for treating certain types of abnormally rapid heart rhythms.
In order to pump blood, the heart request oxygen. The harder the heart works, the extra oxygen it requires. Angina (heart pain) occurs when the supply of oxygen to the heart is insufficient for the amount of work the heart must do. By dilating the arteries, CCBs decrease the pressure in the arteries. This makes it easier for the heart to pump blood, and, as a result, the heart needs a lesser amount of oxygen. Through reducing the heart's need for oxygen, CCBs relieve or prevent angina. CCBs also are used for treating high blood pressure since their blood pressure-lowering effects. CCBs also slow the rate at which the heart beats and are then used for treating certain types of abnormally rapid heart rhythms.
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